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Canker sore prevention?

Question:
Does anyone have advice for the prevention of canker sores in the mouth? I seem to have one after another, sometimes more than one at a time. The total time with is probably greater than the total time without them. If you've ever experienced canker sores you know they can make eating a painful experience. Anytime I bite the inside of my mouth I can be assured that a big one will form. My dention makes this a frequent occurance.
I've seen postings on getting rid of canker sores (with the general consensus that nothing will really get rid of them, only time) but nothing on preventing their occurance or reducing the frequency of their occurance? Should I daily gargle with hydrogen peroxide or mouthwash? Is there anything related to diet, vitamin deficiency or enviroment? I'm not particularly happy with my job, but I don't think I'm under alot of stress. I don't smoke, seldomly drink (beer) and try to eat wholesome foods. Coffee is required at least twice a day, however.


Answer:
Here are a couple of recent thoughts on the prevention of recurrent aphthous stomatitis (canker sores).
It has been noted that smokers and users of smokeless tobacco have significant;y fewer occurrences of aphthous stomatitis. Presumably this is due to the increased keratinization of their oral mucosa, but it may also be a side effect of nicotine. (Note: as a head and neck surgeon, I can assure you that the operations we do for patients with floor of mouth cancers, cancer of the larynx, etc. are a hell of a lot worse than having a few sores in the mouth... therefore, don't smoke or use smokeless tobacco)
Here's a safer alternative that seems to have some efficacy. It's a herbal based tablet enriched with recommended doses of vitamins, called LongoVital. I have never used this and I'm fairly skeptical about vitamin-based therapy, but the literature would seem to suggest some reduction in the occurrence of canker sores is associated with its use (see Journal of Oral Pathology & Medicine, September 1990). It would be interesting to see if vitamin supplementation in general is associated with a decreased incidence.
As for the cause of canker sores... it remains unknown. (There are, however, several condtions associated with higher incindences, such as acute myelogenous leukemia, HIV infection, cyclic neutropenia, etc. All seem to indicate a reduced level of immune competency). My guess? Probably, a virus (varicella-zoster?) is responsible.
I would also hope it goes without saying that not all painful ulcers in the mouth are apthous ulcers, but instead may represent a more serious condition. Any lesion in the mouth lasting longer than 3 weeks probably ought to be seen by an M.D



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