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What causes Canker Sores?

Question:
There's a discussion going on on the vegetarian bulletin board about canker sores, but no one seems to be sure what causes them. The consensus (based mainly on "my doctor said. . .") is that they are caused by a herpes virus, but there seems to be confusion between the lip sores associated with oral herpes, and canker sores inside the mouth. Does anyone out there know what causes canker sores (a virus, bacterium, or multiple causes?)


Answer:
The cause of canker sores (aphthous stomatitis) is not known. It does not seem to be due to herpes viruses, unlike cold sores which are generally caused by herpes simplex virus type I.
There is some evidence that there may be a role for a streptococcal bacteria in causing the sores, and so some people try to prevent recurrences with antibiotic mouth rinses. Presumably the bacteria could trigger an autoimmune response that produces the sores. Topical steroid preparations seem to be helpful if started early after a canker sore begins to develop.



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